ION* Biome

Intelligence
of Nature

Science

At ION*Biome, we have deeply rooted respect for both the Intelligence of Nature and the science that validates it. Dr. Zach Bush and team utilize a state-of-the-art lab to study and substantiate not only the safety, but the efficacy of the entire ION*Biome line.

The following papers demonstrate how Terrahydrite®, the main active ingredient in ION*Biome products, improves tight junction integrity.
  • Protection against Gluten-mediated Tight Junction Injury with a Novel Lignite Extract Supplement
    "Dietary Supplementation of Terrahydrite® Promotes Lysine Production in Healthy Subjects: A Double-Blind, Placebo-Controlled Clinical Trial” shows the ability of ION*Gut Health to promote the gut microbiome production of lysine by which it is expected to play an important role in protein production, epigenetic regulation, collagen production, immune system regulation, and a variety of cell processes.
  • Blood-Brain Barrier Response to Terrahydrite® and Intestinal Gluten Injury
    "Blood-Brain Barrier Response to Terrahydrite® and Intestinal Gluten Injury" shows not only the connection between the microbiome and the gut and blood-brain barrier systems, but also demonstrates the improved effect that Terrahydrite® has on the blood-brain barrier.
  • The Effects of ION*Gut Health Dietary Supplement on Markers of Intestinal Permeability and Immune System Function in Healthy Subjects
    "The Effects of ION*Gut Health Dietary Supplement on Markers of Intestinal Permeability and Immune System Function in Healthy Subjects; A Double-Blind, Placebo-Controlled Clinical Trial" validates the marked effect that ION*Gut Health has on reducing zonulin, IL-6 (an inflammatory marker), and glyphosate in adult humans over a two-week course.
  • Protective Effects of Lignite Extract Supplement on Intestinal Barrier Function in Glyphosate-Mediated Tight Junction Injury
    "Protective Effects of Lignite Extract Supplement on Intestinal Barrier Function in Glyphosate-Mediated Tight Junction Injury" establishes the capacity of Terrahydrite® to block glyphosate-mediated injury in small intestinal and colon epithelial membranes.
  • Protection against Gluten-mediated Tight Junction Injury with a Novel Lignite Extract Supplement
    "Protection against Gluten-mediated Tight Junction Injury with a Novel Lignite Extract Supplement" reveals that the addition of Terrahydrite® stabilizes tight junction integrity even in the face of gluten exposure.